2-IMINOBIOTIN HYDROBROMIDE - Names and Identifiers
2-IMINOBIOTIN HYDROBROMIDE - Physico-chemical Properties
Molecular Formula | C10H18BrN3O2S
|
Molar Mass | 324.23782 |
Storage Condition | 2-8℃ |
In vitro study | Application of low concentrations of 2-Iminobiotin (2-IB; 10 ng/mL and 30 ng/mL) superimposed on hypothermia abrogates the hypoxia-induced lactate dehydrogenase (LDH) increase, resulting in LDH levels that were not different from the normoxia control. |
2-IMINOBIOTIN HYDROBROMIDE - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 3.084 ml | 15.421 ml | 30.841 ml |
5 mM | 0.617 ml | 3.084 ml | 6.168 ml |
10 mM | 0.308 ml | 1.542 ml | 3.084 ml |
5 mM | 0.062 ml | 0.308 ml | 0.617 ml |
Last Update:2024-01-02 23:10:35
2-IMINOBIOTIN HYDROBROMIDE - Reference Information
Biological activity | 2-Iminobiotin hydrobromide (Guanidinobiotin hydrobromide) is a biotin (vitamin H or B7) analog. 2-Iminobiotin hydrobromide is a reversible inhibitor of NO synthase, acting on mouse iNOS and rat n-cNOS with Ki values of 21.8 and 37.5 μM respectively. The 2-Iminobiotin hydrobromide and low temperature environment can protect human nerve cells from hypoxia-induced cell damage. |
target | NO synthases |
Last Update:2024-04-10 22:29:15